Synthesis, characterization and neurotoxicity of schiff bases derived from 1,8-diaminonaphthalene

Six Schiff bases L1-L6 are successfully synthesized by reacting 1,8-diaminonaphthalene with aldehyde and ketone derivatives in the ratio of 1∶2 (amine: aldehyde / ketone). The Schiff bases are characterized using various physical and spectral techniques namely elemental analysis, IR spectroscopy, 1...

Full description

Saved in:
Bibliographic Details
Published in2010 International Conference on Science and Social Research (CSSR 2010) pp. 1287 - 1290
Main Authors Abu Bakar, Ahmad Fauzi, Bahron, Hadariah, Kassim, Karimah, Zain, Mazatulikhma Mat
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.12.2010
Subjects
8-diaminonaphthalene
Color
Compounds
Ethanol
Metals
neurotoxicity
Nuclear magnetic resonance
Protons
Schiff base
Spectroscopy
Online AccessGet full text

Cover

More Information
Summary:Six Schiff bases L1-L6 are successfully synthesized by reacting 1,8-diaminonaphthalene with aldehyde and ketone derivatives in the ratio of 1∶2 (amine: aldehyde / ketone). The Schiff bases are characterized using various physical and spectral techniques namely elemental analysis, IR spectroscopy, 1 H NMR spectroscopy and melting point determination. The neurotoxicity of the compounds is evaluated using neuroblastoma SH-SY5Y cell lines at which they are indicated to be non-toxic.
ISBN:9781424489879
1424489873
DOI:10.1109/CSSR.2010.5773736