Highly sensitive and selective label-free detection of cardiac biomarkers in blood serum with silicon nanowire biosensors

Arrays of highly ordered silicon nanowire (SiNW) are fabricated using complementary metal-oxide semiconductor (CMOS) field effect transistor-compatible technology, and the ultrasensitive, label-free, electrical detection of cardiac biomarker in blood serum using the array sensor is demonstrated. The...

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Bibliographic Details
Published in2009 IEEE International Electron Devices Meeting (IEDM) pp. 1 - 4
Main Authors Guo-Jun Zhang, Luo, Z.H.H., Min Joon Huang, Tay, G.K.I., Lim, E.-J.A., Yu Chen
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.12.2009
Subjects
Biomarkers
Biosensors
Blood
Nanobioscience
Nanoscale devices
Optical sensors
Sensor arrays
Silicon
Surface resistance
Surface treatment
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Summary:Arrays of highly ordered silicon nanowire (SiNW) are fabricated using complementary metal-oxide semiconductor (CMOS) field effect transistor-compatible technology, and the ultrasensitive, label-free, electrical detection of cardiac biomarker in blood serum using the array sensor is demonstrated. The SiNW array biosensor allows for real-time detection of cardiac biomarker in desalted serum, more importantly, multiplexed detection of cardiac biomarkers in untreated and non-desalted blood serum.
ISBN:9781424456390
1424456398
ISSN:0163-1918
2156-017X
DOI:10.1109/IEDM.2009.5424265