Broad-band Mach-Zehnder Interferometry as a detection principle for label-free biochemical sensing

In this work the Broad-Band Mach-Zehnder Interferometry (BB-MZI) is presented as an alternative operation principle for optical biochemical sensors that will allow for ultra-sensitive, label-free, multi-analyte detection schemes. Simulation studies were performed for a Si-based MZI so as to explore...

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Bibliographic Details
Published in2008 IEEE Sensors pp. 934 - 937
Main Authors Kitsara, M., Raptis, I., Misiakos, K., Makarona, E.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.10.2008
Subjects
Biomedical optical imaging
Biosensors
Optical interferometry
Optical refraction
Optical ring resonators
Optical sensors
Optical surface waves
Optical variables control
Optical waveguides
Refractive index
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Summary:In this work the Broad-Band Mach-Zehnder Interferometry (BB-MZI) is presented as an alternative operation principle for optical biochemical sensors that will allow for ultra-sensitive, label-free, multi-analyte detection schemes. Simulation studies were performed for a Si-based MZI so as to explore its sensing capabilities in terms of the transmission output spectrum. The presented simulation results concern biochemical applications such as aqueous glucose solutions and hypothetical thin protein adlayers adsorbed on the sensing arm.
ISBN:1424425808
9781424425808
ISSN:1930-0395
2168-9229
DOI:10.1109/ICSENS.2008.4716594