Development of Whole Human Genome Micro-array Automated Hybridization Platform

A micro-array based automated hybridization platform, ITRI HybOne, has been developed for whole human genome expression profiling test. According to the user-defined protocol, an operator can set the heating temperature, washing temperature, heating hours and washing hours before starting the profil...

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Bibliographic Details
Published in2007 IEEE International Conference on Automation Science and Engineering pp. 640 - 645
Main Authors Jinq-Yu Jiang, Kuo-Hsiung Lin, Chia-Chun Chen, Jie-Len Huang, Chun-Hung Huang, Hung-Ju Su
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.09.2007
Subjects
Automation
Bioinformatics
Biomedical engineering
DNA
Genomics
Heating
Humans
Machining
Prototypes
Throughput
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Summary:A micro-array based automated hybridization platform, ITRI HybOne, has been developed for whole human genome expression profiling test. According to the user-defined protocol, an operator can set the heating temperature, washing temperature, heating hours and washing hours before starting the profiling test. Operator inputs target samples and micro-arrays to ITRI HybOne and push the Cycle-Start button to start. After hours of automatic process, the micro-arrays are ready for profile scanning. The prototype platform has a throughput rate of 12-sets of hybridization per lot.
ISBN:9781424411535
142441153X
ISSN:2161-8070
2161-8089
DOI:10.1109/COASE.2007.4341797