Transient electropore lifetimes in skeletal muscle cells
Electroporation of skeletal muscle cell membranes has been postulated to cause myonecrosis in most victims of major electrical trauma. (1,2) To precisely quantify membrane damage due to electroporation, we utilized a ratiometric fluorometric assay to determine the threshold of imposed transmembrane...
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Published in | 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 1; pp. 304 - 306 |
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Main Authors | , , |
Format | Conference Proceeding |
Language | English |
Published |
IEEE
01.10.1992
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Subjects | |
Online Access | Get full text |
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Summary: | Electroporation of skeletal muscle cell membranes has been postulated to cause myonecrosis in most victims of major electrical trauma. (1,2) To precisely quantify membrane damage due to electroporation, we utilized a ratiometric fluorometric assay to determine the threshold of imposed transmembrane potential required to reversibly and irreversibly electroporate the cell membrane and calculated the time constants for electropores created over a wide range of applied fields. |
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ISBN: | 0780307852 9780780307858 |
DOI: | 10.1109/IEMBS.1992.5760977 |