Detection and characterization of early atherosclerosis

Early stages of atherosclerosis in human subjects can be detected by lumen diameter and the pressure-strain elastic modulus. Results from non-human primate studies show that the intima thickens increasing the area enclosed by the elastic lamina. During this time the artery dilates so that the lumen...

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Bibliographic Details
Published inThe seventh Annual Symposium on Computer Applications in Medical Care, 1983 : proceedings : 23-26 October 1983 pp. 797 - 803
Main Authors Barnes, R.W., Bond, M.G., Riley, W.A., Czapla, L., Mazzola, C.J., Birdwell, J.O.
Format Conference Proceeding
LanguageEnglish
Published IEEE 1983
Subjects
Arteries
Atherosclerosis
Blood pressure
Bonding
Educational institutions
Humans
IEL
Pulse generation
Testing
Thickness measurement
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ISBN9780818605031
0818605030
DOI10.1109/SCAMC.1983.764772

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Summary:Early stages of atherosclerosis in human subjects can be detected by lumen diameter and the pressure-strain elastic modulus. Results from non-human primate studies show that the intima thickens increasing the area enclosed by the elastic lamina. During this time the artery dilates so that the lumen area remains essentially constant. Only after the artery reaches its elastic limit does the lumen area decrease. Accurate measurements of arterial wall thickness and lumen diameter at diastole are important to the early detection of atherosclerosis. Axial resolutions of less than 0.1mm are required to detect tissue layers within the arterial wall itself. Two approaches and results of high axial resolution, deconvolution and high axial pulse generation, meeting range resolution requirements are presented.
ISBN:9780818605031
0818605030
DOI:10.1109/SCAMC.1983.764772