A simple and efficient protocol for the synthesis of quinoxaline derivatives using recyclable H5PW6Mo4V2O40·14H2O catalyst

• Published in: Synthetic communications Vol. 52; no. 11-12; pp. 1379 - 1388
• Main Authors: Aher, Dipak S., Khillare, Kiran R., Chavan, Laxmikant D., Shelke, Vinod A., Shankarwar, Sunil G.
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis 18.06.2022; Taylor & Francis Ltd
• Subjects: Aromatic compounds; Benzil; Catalysis; Catalysts; Catalytic activity; Chemical synthesis; Ethanol; green chemistry; heteropoly acids; homogeneous; Phenylenediamine; quinoxaline; Quinoxalines; Reaction time; Substitutes
• ISSN: 0039-7911; 1532-2432
• DOI: 10.1080/00397911.2022.2093645

Vanadium substituted Molybdotungstophosphoric acid (H 5 PW 6 Mo 4 V 2 O 40 ·14H 2 O) was observed to be an effective solid catalyst for one-pot synthesis of several quinoxaline derivatives from the condensation reaction between various substituted o-phenylenediamine and various aromatic benzil compounds in ethanol: water (1:1) solvent under the reflux condition. The catalytic activity was tested under different reaction conditions to know the performance of the synthesized catalysts. Excellent yield, short reaction time, simple workup procedure, and reusability of the catalyst are the prominent features of our synthetic route. We report a series of vanadium substituted molybdotungstophosphoric acid, H 5 [PW 6 Mo 4 V 2 O 40 ]·14H 2 O as a catalyst for the synthesis of quinoxaline derivatives.