Design and Investigation of Photonic Crystal Fiber for the Detection of HIV Virus

• Published in: 2022 Smart Technologies, Communication and Robotics (STCR) pp. 1 - 5
• Main Authors: Mahalakshmi, S., Nizar, S. Mohamed, Elizabeth Caroline, B., Sagadevan, K., Loga, K.
• Format: Conference Proceeding
• Language: English
• Published: IEEE 10.12.2022
• Subjects: AIDS; Biological system modeling; biosensor; Confinement Loss (α CL ); HIV virus; Human immunodeficiency virus; immune system; Photonic crystal fibers; Photonic Crystal Fibre; Relative Sensitivity(R s ); Robot sensing systems; Sensitivity; Sensors; Software
• DOI: 10.1109/STCR55312.2022.10009132

PCF is a photonic crystal-based optical fibre. For sensing HIV (Human Immunodeficiency Virus) in the human body, a photonic crystal fiber-based biosensor is proposed.The hollow core photonic crystal fibre (HCPCF) is utilised in this article to elucidate the HIV virus contaminated cells in the body. This model gives higher sensitivity in detecting contaminated HIV virus by minimising confinement loss. To analyse the output of the PCF sensor the Sample cells are inserted in the core.The hollow core with air ring enhances the sensing for biomedical analytes.Relative Sensitivity(R s ), Effective mode area (A eff ), Confinement loss (α CL ) and effective mode index can be determined by using this Comsol multiphysics software. This Software is used to design the high complexity fabrication model.Pathogen impacts the defensive mechanism of the human individual.AIDS (acquired immunodeficiency syndrome) can develop from HIV if it is not adequately managed). To examine the PCF sensor's operation, sample cells typically placed into the core. The hollow core with air ring optimizes the sensing of biological analytes. At Certain Wavelength the laser light passes through a core. This Software is employed in construct the high complexity fabrication.TheHIV pathogen develops the HIV/AIDS epidemic spectrum.The human immune system's CD4+ T cells, macrophages, and dendritic cells are frequently contaminated by that of the retrovirus designated as HIV. It suppresses CD4+ T cells both intrinsically and extrinsically. The three levels of HIV infectioncompriseof acute, chronic, and acquired immunodeficiency syndrome (AIDS).Although there is no cure for HIV, medication can help to standstill or quit the progression of the disease. Antiretroviral therapy is a type of treatment for HIV infection (ART). HIV is spurred on by a virus. Through sexual contact, illicit drug use, reusing needles,in touch with contaminated blood, or contact with infected blood, it can be spread from mother to infant, delivery, or suckling. HIV attacks CD4 T cells, is some kind of white blood cell that is essential for disease resistance. The design of the previous work is quite complicated and lacks precision. So, using the COMSOL Multiphysics software, we created a basic structure PCF-based Bio Sensor for HIV sensing. We reached a relative sensitivity of around 96.827 for wavelengthλ = 0.7m by interpreting the simulation findings. Our concept appears to be fairly basic and accuratepremised on the results we have obtained.