Investigation of a combined absorption-fluorescence-Raman spectroscopy approach to brain tumor tissue differentiation ex vivo

In this work, we used a combined absorption-fluorescence-Raman approach to the optical investigation of brain tissue. The proposed approach allowed taking into account the blood fill, oxygenation, accumulation of fluorescent biomarker, and Raman signal to estimate a degree of malignancy of the tissu...

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Bibliographic Details
Published in2022 International Conference Laser Optics (ICLO) p. 1
Main Authors Romanishkin, I.D., Savelieva, T.A., Poletaeva, I.Yu, Shugai, S.V., Goryaynov, S.A., Golbin, D.A., Loschenov, V.B.
Format Conference Proceeding
LanguageEnglish
Published IEEE 20.06.2022
Subjects
absorption
Biomedical optical imaging
Blood
Brain
brain tumor
Fluorescence
Integrated optics
Lasers
photodiagnostics
protoporphyrin
Raman spectroscopy
Spectroscopy
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Summary:In this work, we used a combined absorption-fluorescence-Raman approach to the optical investigation of brain tissue. The proposed approach allowed taking into account the blood fill, oxygenation, accumulation of fluorescent biomarker, and Raman signal to estimate a degree of malignancy of the tissue.
ISBN:1665466634
9781665466639
ISSN:2642-5580
DOI:10.1109/ICLO54117.2022.9840141