Validation of predictive equations for resting energy expenditure in Japanese pediatric Crohn's disease patients: Preliminary study

• Published in: Pediatrics international Vol. 57; no. 2; pp. 290 - 294
• Main Authors: Arai, Katsuhiro, Funayama, Rie, Takahashi, Mieko, Sakai, Rie, Shimizu, Hirotaka, Obayashi, Naho, Matsui, Akira
• Format: Journal Article
• Language: English
• Published: Australia Blackwell Publishing Ltd 01.04.2015
• Subjects: Adolescent; Asian Continental Ancestry Group; Bland-Altman plot; Body Composition; Calorimetry, Indirect - methods; Child; Crohn Disease - physiopathology; Crohn's disease; Crohns disease; Diet; Energy Metabolism - physiology; Female; Humans; Japan; Japanese Dietary Reference Intakes; Male; Pediatrics; predictive equation; Predictive Value of Tests; Regression Analysis; resting energy expenditure; Japan, Honshu, Tokyo Prefect., Tokyo; predictive equation; resting energy expenditure; Crohn's disease; Japanese Dietary Reference Intakes; Bland-Altman plot
• ISSN: 1328-8067; 1442-200X
• DOI: 10.1111/ped.12504

Background Predictive equations are often used to estimate resting energy expenditure (REE). Determining the appropriate equation for different patient types, however, remains inconclusive, as in the case of Japanese children with Crohn's disease (CD). The aim of this study was to identify an appropriate predictive equation for measuring REE in Japanese children with CD. Methods Twelve Japanese children with CD managed at the National Center for Child Health and Development in Tokyo, Japan, were studied. REE (kcal/day) was measured using indirect calorimetry. The predictive equations used were the Japanese Dietary Reference Intakes (2010), the Schofield equation, the Food and Agriculture Organization/World Health Organization/United Nations University (FAO/WHO/UNU) equation and the Cunningham equation. Difference between predicted and measured REE was analyzed on Bland–Altman plot. Results Japanese Dietary Reference Intakes (2010) had the smallest difference between predicted and measured REE. Weight was the primary predictor of REE on multiple regression analysis. As well, Japanese Dietary Reference Intakes (2010) had the highest ratio of weight to predicted REE (98.5%). Conclusions Of the four equations, Japanese Dietary Reference Intakes (2010) appeared to be the most practical and accurate predictive equation for REE in Japanese children with CD.