Effect of Cultivation Conditions on the Structure and Morphological Properties of BNC Biomaterials with a Focus on Vascular Grafts

20New materials that are not thrombogenic and have mechanical properties that mimic the native blood vessel are in very great demand. Nanocellulose produced by the bacteria Gluconacetobacter xylinus is a biomaterial that has gained interest in the field of tissue engineering because of its unique pr...

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Bibliographic Details
Published inBacterial NanoCellulose pp. 19 - 42
Main Authors Gatenholm, Paul, Höglund, Kim, Johannesson, Sara, Puchades, Maja, Brackmann, Christian, Enejder, Annika, Olsson, Lisbeth
Format Book Chapter
LanguageEnglish
Published United States CRC Press 2012
Taylor & Francis Group
Edition1
Subjects
Biomedical engineering
Biotechnology
Materials science
Double Network Gels
Cellulose Synthesis
Bacterial Cellulose Production
Bacterial Cellulose
Cellulose Network
Acetobacter Xylinum
Vascular Grafts
Tris Hydroxymethyl Aminomethane
Fructose-1 Phosphate Kinase
Cellulose Tube
Polysaccharides
Cellulose Production
BNC
Poly Saccharides
Cellulose Synthase
Sweet Corn
PPy
SHG Image
PPy Composite
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Summary:20New materials that are not thrombogenic and have mechanical properties that mimic the native blood vessel are in very great demand. Nanocellulose produced by the bacteria Gluconacetobacter xylinus is a biomaterial that has gained interest in the field of tissue engineering because of its unique properties, such as great mechanical strength, high water content (around 99%), and the ability to be shaped into three-dimensional structures during biosynthesis. The fabrication process of bacterial nanocellulose (BNC) vascular grafts is very unique because the material synthesis and product formation takes place simultaneously. The bio mechanical performance, which includes rupture pressure and compliance along with biological response (endothelialization, blood compatibility, etc.), is dependent on the morphology of a fibrillar network. The network formation is affected by cellulose assembly and bacteria motion, proliferation rate, and other factors. An understanding of the effects of cultivation conditions on BNC network formation is therefore of great importance.
ISBN:1138073164
143986991X
9781138073166
9781439869918
9781439869925
1439869928
DOI:10.1201/b12936-3