The development of specific IgG4 after immunotherapy with standardized extracts

A significant reduction in symptoms scores was observed in those patients who elected to continue their immunotherapy after achieving maintenance. All of those patients developed allergen specific IgG4 within a year of post-maintenance injections. These findings suggest that a reduction of allergic...

Full description

Saved in:
Bibliographic Details
Published inAllergy and asthma proceedings Vol. 8; no. 6; pp. 429 - 435
Main Authors Harris, N S, Rock, H S, Leese, P T
Format Journal Article
LanguageEnglish
Published United States OceanSide Publications 01.11.1987
Subjects
Adolescent
Adult
Aged
Allergens - administration & dosage
Allergens - immunology
Clinical Trials as Topic
Desensitization, Immunologic
Female
Humans
Hypersensitivity - immunology
Hypersensitivity - therapy
Immunoassay
Immunoglobulin E - biosynthesis
Immunoglobulin G - biosynthesis
Immunoglobulin G - classification
Male
Middle Aged
Online AccessGet full text

Cover

More Information
Summary:A significant reduction in symptoms scores was observed in those patients who elected to continue their immunotherapy after achieving maintenance. All of those patients developed allergen specific IgG4 within a year of post-maintenance injections. These findings suggest that a reduction of allergic symptoms is accompanied by a rise in specific IgG4 antibody against the offending allergen(s). These specific IgG4 antibodies can be induced by appropriate immunotherapy. Lastly, allergen specific IgG4 antibodies were rapidly and accurately determined using the 3M IgG4 FAST test.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ISSN:0742-2814
1088-5412
1539-6304
DOI:10.2500/108854187778999586