8-methoxypsoralen plus UVA (PUVA) therapy normalizes signalling of phosphorylated component of mTOR pathway in psoriatic skin of K5.hTGFβ1 transgenic mice

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Bibliographic Details
Published inExperimental dermatology Vol. 24; no. 11; pp. 889 - 891
Main Authors Shirsath, Nitesh, Mayer, Gerlinde, Singh, Tej Pratap, Wolf, Peter
Format Journal Article
LanguageEnglish
Published Denmark Blackwell Publishing Ltd 01.11.2015
Subjects
Animals
mammalian target of rapamycin (mTOR)
Mice, Transgenic
Phosphorylation
psoralen
psoriasis
Psoriasis - metabolism
Psoriasis - therapy
PUVA
PUVA Therapy
Ribosomal Protein S6 - metabolism
TOR Serine-Threonine Kinases - metabolism
transgenic mouse model
mammalian target of rapamycin (mTOR)
psoralen
PUVA
transgenic mouse model
psoriasis
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Bibliography:PhD program of Medical University of Graz
istex:4079177446F39113FFF842D700B877B720591DFF
ark:/67375/WNG-0M3H44WX-0
ArticleID:EXD12779
Data S1. Materials and Methods.Figure S1. The staining intensity of EGFR (receptor for members of the epidermal growth factor) is slightly upregulated in psoriatic epidermis of K5.hTGFß1 transgenic (TG) mice (c) compared to wild type mice (WT) (a) and PUVA-treated mice (e). Control IgG, isotype antibody staining (b, d, f). Scale bar, 50 μm.Data S2. References.Table S1. List of primary antibodies.
Austrian Science Fund (FWF) - No. W1241-B18
SourceType-Other Sources-1
ObjectType-Article-2
content type line 63
ObjectType-Correspondence-1
ISSN:0906-6705
1600-0625
DOI:10.1111/exd.12779