Effect on BOLD sensitivity due to susceptibility-induced echo time shift in spiral-in based functional MRI

Susceptibility artifacts induced by the magnetic field inhomogeneity exist near the air/tissue interfaces at the ventral brain in functional magnetic resonance imaging (fMRI). These susceptibility artifacts will cause geometric distortions and signal loss in reconstructed images. Additionally, the i...

Full description

Saved in:
Bibliographic Details
Published in2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society Vol. 2009; pp. 4449 - 4452
Main Authors Yue Zhuo, Sutton, B.P.
Format Conference Proceeding Journal Article
LanguageEnglish
Published United States IEEE 01.01.2009
Subjects
Brain - physiology
Distortion measurement
Extraterrestrial measurements
Humans
Image reconstruction
Magnetic analysis
Magnetic field measurement
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Magnetic susceptibility
Models, Theoretical
Oxygen - blood
RF signals
Signal analysis
Signal Processing, Computer-Assisted
Tellurium
Online AccessGet full text

Cover

More Information
Summary:Susceptibility artifacts induced by the magnetic field inhomogeneity exist near the air/tissue interfaces at the ventral brain in functional magnetic resonance imaging (fMRI). These susceptibility artifacts will cause geometric distortions and signal loss in reconstructed images. Additionally, the in-plane susceptibility gradients will cause a shift in effective echo time, and therefore influence the blood-oxygen-level dependent (BOLD) sensitivity since it is proportional to effective echo time. In this work, we examine the effective echo time shift and the change of the BOLD sensitivity based on susceptibility gradients. The analysis results show that there are regions, such as the orbitofrontal cortex, that suffer from significant loss of BOLD sensitivity using spiral-in trajectory in BOLD fMRI.
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/IEMBS.2009.5333815