Relationship between the Tumor Necrosis Factor System and the Serum Interleukin-4, Interleukin-5, Interleukin-8, Eosinophil Cationic Protein, and Immunoglobulin E Levels in the Bronchial Hyperreactivity of Adults and Their Children
The aim of the study was to investigate the activation of inflammatory mediators interleukin (IL)-4, IL-5, and IL-8; immunoglobulin E (IgE); and eosinophil cationic protein (ECP) and to evaluate the regulatory role of the tumor necrosis system (TNF) system in bronchial hyperreactivity. Adults who ha...
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Published in | Allergy and asthma proceedings Vol. 24; no. 2; pp. 111 - 118 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
United States
OceanSide Publications, Inc
01.03.2003
OceanSide Publications |
Subjects | |
Online Access | Get full text |
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Summary: | The aim of the study was to investigate the activation of inflammatory mediators interleukin (IL)-4, IL-5, and IL-8; immunoglobulin E (IgE); and eosinophil cationic protein (ECP) and to evaluate the regulatory
role of the tumor necrosis system (TNF) system in bronchial hyperreactivity. Adults who had suffered from bronchial asthma in childhood but who had been symptom free for at least 3 years were examined together
with their children who did not have asthma. The serum concentrations of TNF-α, soluble TNF receptor 1 (sTNF-R1), TNF-R2, IL-4, IL-5, IL-8, ECP, and IgE were studied in symptom-free adults (n = 22)
and their children (n = 22) with bronchial hyperreactivity. Nonhyperreactive individuals with a similar medical history |
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Bibliography: | (RF) Otorhinolaryngology 1088-5412(20030301)24:2L.111;1- ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1088-5412 1539-6304 |