Spontaneous Resolution of a Central Giant Cell Granuloma in a Child After an Incisional Biopsy: A Five-year Follow-up

A central giant cell granuloma (CGCG) is typically regarded as a benign lesion with osteoclastic activity. Treatment often involves surgical procedures that may cause deformities; however, minimally invasive approaches have been suggested for treating pediatric patients. We report a case of CGCG of...

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Published inJournal of dentistry for children (Chicago, Ill.) Vol. 83; no. 2; p. 102
Main Authors Franco, Ademir, Segato, André V K, Couto, Soraya A B, Rodrigues Johann, Aline Cristina Batista, Friedlander, Arthur H, Couto Souza, Paulo H
Format Journal Article
LanguageEnglish
Published United States 01.05.2016
Subjects
Adolescent
Biopsy
Diagnosis, Differential
Follow-Up Studies
Granuloma, Giant Cell - diagnostic imaging
Granuloma, Giant Cell - pathology
Humans
Male
Mandibular Diseases - diagnostic imaging
Mandibular Diseases - pathology
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Summary:A central giant cell granuloma (CGCG) is typically regarded as a benign lesion with osteoclastic activity. Treatment often involves surgical procedures that may cause deformities; however, minimally invasive approaches have been suggested for treating pediatric patients. We report a case of CGCG of the mandible in a 13-year-old boy who presented with a well-defined radiolucent area in the anterior mandible that was initially detected in a radiographic examination for orthodontic purposes. An incisional biopsy was performed and diagnosed histologically as a CGCG. The patient underwent clinical and radiographic follow-up only after the biopsy, eventually showing signs of bone healing. Five years later, complete resolution of the lesion was observed radiographically. Considering this optimal outcome, similar cases of CGCG should be carefully analyzed for appropriateness of this conservative approach.
ISSN:1935-5068