Spontaneous patterning obtained by evaporation of Human Elastin-like Polypeptide solutions

The potential of producing patterned, bioactive coatings with Human Elastin-Like Polypeptides (HELPs) has been investigated. The physicochemical features of these compounds have evidenced some differences between the two recombinantly expressed products. By a device-free, simple route and avoiding t...

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Bibliographic Details
Published in2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Vol. 2010; pp. 819 - 822
Main Authors Bandiera, A, Urbani, R, Sist, P
Format Conference Proceeding Journal Article
LanguageEnglish
Published United States IEEE 01.01.2010
Subjects
Binding Sites
Coated Materials, Biocompatible - chemical synthesis
Coatings
Desiccation
Elastin - chemistry
Geometry
Humans
Materials Testing
Peptides - chemistry
Polymers
Protein Binding
Solutions
Surface morphology
Surface treatment
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Summary:The potential of producing patterned, bioactive coatings with Human Elastin-Like Polypeptides (HELPs) has been investigated. The physicochemical features of these compounds have evidenced some differences between the two recombinantly expressed products. By a device-free, simple route and avoiding the use of chemically unfriendly compounds, micropatterned surfaces with the ability to control cell behavior could be obtained. Thus, HELPs represent a very promising class of macromolecule for future applications in surface engineering.
ISBN:1424441234
9781424441235
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/IEMBS.2010.5626761