Physiological control of implantable rotary blood pumps for heart failure patients

In general, patient variability and diverse environmental operation makes physiological control of a left ventricular assist device (LVAD) a complex and complicated problem. In this work, we implement a Starling-like controller which adjusts mean pump flow using pump flow pulsatility as the feedback...

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Published in2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Vol. 2013; pp. 675 - 678
Main Authors Bakouri, Mohsen A., Salamonsen, Robert F., Savkin, Andrey V., Alomari, Abdul-Hakeem H., Einly Lim, Lovell, Nigel H.
Format Conference Proceeding Journal Article
LanguageEnglish
Published United States IEEE 01.01.2013
Subjects
Algorithms
Blood
Computer Simulation
Control systems
Educational institutions
Electronic mail
Feedback
Heart
Heart Failure - physiopathology
Heart Failure - therapy
Heart Ventricles - physiopathology
Heart-Assist Devices
Humans
Mathematical model
Models, Cardiovascular
Physiology
Pulsatile Flow
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Summary:In general, patient variability and diverse environmental operation makes physiological control of a left ventricular assist device (LVAD) a complex and complicated problem. In this work, we implement a Starling-like controller which adjusts mean pump flow using pump flow pulsatility as the feedback parameter. The linear relationship between mean pump flow and pump flow pulsatility forms the desired flow of the Starling-like controller. A tracking control algorithm based on sliding mode control (SMC) has been implemented. The controller regulates the estimated mean pulsatile flow (Q̅ p ) and flow pulsatility (PI Qp ) generated from a model of the assist device. A lumped parameter model of the cardiovascular system (CVS) was used to test the control strategy. The immediate response of the controller was evaluated by inducing a fall in left ventricle (LV) preload following a reduction in circulating blood volume. The simulation supports the speed and robustness of the proposed strategy.
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/EMBC.2013.6609590