Multidrug-resistant tuberculosis in Denmark 1993-1995
SETTING: All bacteriologically confirmed new cases of tuberculosis and treatment relapses in Denmark are examined for drug resistance. In the years 1993-1995, nine cases of multidrug-resistant tuberculosis (MDR-TB), all acquired outside Denmark, were identified among 1354 cases of tuberculosis.OBJEC...
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Published in | The international journal of tuberculosis and lung disease Vol. 1; no. 4; pp. 299 - 301 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Paris, France
IUATLD
01.08.1997
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Subjects | |
Online Access | Get full text |
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Summary: | SETTING: All bacteriologically confirmed new cases of tuberculosis and treatment relapses in Denmark are examined for drug resistance. In the years 1993-1995, nine cases of multidrug-resistant tuberculosis (MDR-TB), all acquired outside Denmark, were identified among 1354 cases
of tuberculosis.OBJECTIVE: To examine incidence, treatment and prognosis for patients with tuberculosis due to MDR Mycobacterium tuberculosis.DESIGN: Retrospective evaluation of routine data.RESULTS AND CONCLUSION: Multidrug resistance was present in less than one percent
of patients with tuberculosis. One patient died from tuberculosis without revision of treatment, and eight patients responded favourably to a regimen of pyrazinamide, streptomycin or amikacin, ofloxacin and cycloserine. In two patients, this regimen was supplemented with para-aminosalicylic
acid and thiacetazone respectively. All patients needed prolonged hospitalization and had observed treatment. It is possible to cure such patients, but it is a lengthy and expensive process. It is expected that similar cases will be imported into the country and that they will occur within
Denmark in the future. |
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Bibliography: | (R) Medicine - General 1027-3719(19970801)1:4L.299;1- ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 1027-3719 1815-7920 |