One-Pot, Three-Component Synthesis of Cis-Isoquinolonic Acids Using ZnCl2, AlCl3-SiO2 as Catalyst

Abstract ZnCl 2 , AlCl 3 -SiO 2 catalyzes efficiently the three-component condensation reaction of aldehydes, amines, and homophthalic anhydride in dichloromethane to afford the corresponding cis-isoquinolonic acids in good yields at room temperature.

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Bibliographic Details
Published inSynthetic communications Vol. 41; no. 4; pp. 523 - 527
Main Authors Mohammadi, Mohammad Hassan, Mohammadi, Ali A.
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis 01.01.2011
Taylor & Francis Ltd
Subjects
Acids
Chemistry
Chemistry, Organic
Cis-isoquinolonic acids
homophthalic anhydride
multicomponent condensations
Physical Sciences
Science & Technology
ZnCl2, AlCl3-SiO2
ZnCl2
IMINES
multicomponent condensations
AGENTS
AlCl3-SiO2
homophthalic anhydride
DERIVATIVES
Cis-isoquinolonic acids
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Summary:Abstract ZnCl 2 , AlCl 3 -SiO 2 catalyzes efficiently the three-component condensation reaction of aldehydes, amines, and homophthalic anhydride in dichloromethane to afford the corresponding cis-isoquinolonic acids in good yields at room temperature.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911003611786