Neoclerodane Diterpenoids from Teucrium maghrebinum

• Published in: Journal of natural products (Washington, D.C.) Vol. 63; no. 7; pp. 1029 - 1031
• Main Authors: BRUNO, Maurizio, BONDì, Maria L., ROSSELLI, Sergio, PIOZZI, Franco, AL-HILLO, Malik R. Y., LAMARA, Kaddour, LADJEL, Segni
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.07.2000; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: Biological and medical sciences; Chemistry, Medicinal; Diterpenes - chemistry; Diterpenes - isolation & purification; General pharmacology; Lamiaceae - chemistry; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Medical sciences; Molecular Structure; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Plant Sciences; Science & Technology; Morocco; Algeria; Africa; NEO-CLERODANE DITERPENOIDS; FURANOID DITERPENES; FUROCLERODANES; Epimer; Furan derivatives; Oxygen heterocycle; Antimicrobial agent; Medicinal plant; Folk medicine; Dicotyledones; Angiospermae; Antifeedant; Secondary alcohol; Acylate; Terpenoid; Pharmacognosy; Lactone; Tetracyclic compound; Tricyclic compound; Spiran; Primary alcohol; Labiatae; Plant origin; Diterpene; Isolation; Above ground plant part; Spermatophyta; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np990510a

Eight neoclerodane diterpenoids were identified in the extract of the aerial parts of Teucrium maghrebinum. Three of these, 12-epi-teucjaponin A (1), 12-epi-montanin D (2), and 12-epi-montanin B (3), are new natural products, whereas five, teucjaponin A, montanin D, 19-deacetylteuscorodol, teusalvin C (4), and montanin B, are already known. These eight compounds form four pairs of epimers at carbon C-12.