Diterpenoids from the Leaves of Juniperus chinensis var. kaizuka

• Published in: Journal of natural products (Washington, D.C.) Vol. 64; no. 4; pp. 511 - 514
• Main Authors: LEE, Ching-Kuo, CHENG, Yu-Shia
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society 01.04.2001; Amer Chemical Soc; American Society of Pharmacognosy
• Subjects: Biological and medical sciences; Chemistry, Medicinal; Crystallography, X-Ray; Diterpenes - chemistry; Diterpenes - isolation & purification; General pharmacology; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Medical sciences; Models, Molecular; Molecular Structure; Pharmacognosy. Homeopathy. Health food; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Plant Leaves - chemistry; Plant Sciences; Plants, Medicinal - chemistry; Science & Technology; Asia; China; Pentacyclic compound; Terpenoid; Pharmacognosy; Oriental medicine; Lactone; Plant leaf; Aldehyde; Tricyclic compound; Enaldehyde; Oxygen heterocycle; Medicinal plant; Folk medicine; Gymnospermae; Juniperus chinensis; Plant origin; Bicyclic compound; Diterpene; Isolation; Coniferales; Spermatophyta; Aromatic compound; Structural analysis
• ISSN: 0163-3864; 1520-6025
• DOI: 10.1021/np0004505

Two diterpenoids based on novel carbon skeletons, namely, 8,19-dioxo-8, 14-seco-chinan-14,11-olide (1) and 8-oxo-8, 14-seco-abiet- 12-en- 14,19-dial (2), have been isolated, together with two new abietene diterpenoids, 13 beta ,14 beta -epoxyabiet-7-en-19,6 beta -olide (3) and 7 beta -hydroxyabieta-8,11,13-trien-19-al (4), from the leaves of Juniperus chinensis. Their structures were determined by spectroscopic methods, including 2D NMR, and, in the case of 1, X-ray crystallographic analysis.