Design of Bioprosthetic Aortic Valves using biaxial test data

• Published in: 2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Vol. 2015; pp. 3319 - 3322
• Main Authors: Dabiri, Y., Paulson, K., Tyberg, J., Ronsky, J., Ali, I., Di Martino, E., Narine, K.
• Format: Conference Proceeding Journal Article
• Language: English
• Published: United States IEEE 01.01.2015
• Subjects: Aortic Valve - physiology; Computer Simulation; Finite Element Analysis; Geometry; Heart Valve Prosthesis; Mathematical model; Numerical models; Prosthesis Design; Strain; Stress; Stress, Mechanical; Tensile Strength; Valves
• ISSN: 1094-687X; 1557-170X; 1558-4615
• DOI: 10.1109/EMBC.2015.7319102

Bioprosthetic Aortic Valves (BAVs) do not have the serious limitations of mechanical aortic valves in terms of thrombosis. However, the lifetime of BAVs is too short, often requiring repeated surgeries. The lifetime of BAVs might be improved by using computer simulations of the structural behavior of the leaflets. The goal of this study was to develop a numerical model applicable to the optimization of durability of BAVs. The constitutive equations were derived using biaxial tensile tests. Using a Fung model, stress and strain data were computed from biaxial test data. SolidWorks was used to develop the geometry of the leaflets, and ABAQUS finite element software package was used for finite element calculations. Results showed the model is consistent with experimental observations. Reaction forces computed by the model corresponded with experimental measurements when the biaxial test was simulated. As well, the location of maximum stresses corresponded to the locations of frequent tearing of BAV leaflets. Results suggest that BAV design can be optimized with respect to durability.