Synthesis and biological activities of new 1H-1,2,4-triazole alcohol derivatives containing a ferrocenyl moiety

• Published in: Applied organometallic chemistry Vol. 22; no. 4; pp. 237 - 241
• Main Authors: Liu, Jianbing, Li, Lichun, Dai, Hong, Fang, Jianxin
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.04.2008
• Subjects: 1H-1; 1H‐1,2,4‐triazole; 4-triazole; antifungal activity; ferrocenyl moiety; plant growth regulatory activity; synthesis
• ISSN: 0268-2605; 1099-0739
• DOI: 10.1002/aoc.1380

Fourteen new 1H‐1,2,4‐triazole alcohol derivatives containing a ferrocenyl moiety were synthesized. In addition, six unexpected compounds, the hydroxyls of the title compounds, methylated by methanol, were obtained. The structures of all these new compounds were confirmed using 1H NMR spectra, 13C NMR, MS and elemental analyses. Some compounds were also confirmed with IR spectra. The antifungal and plant growth regulatory activities of the title compounds are discussed. Copyright © 2008 John Wiley & Sons, Ltd. Fourteen new 1H‐1,2,4‐triazole alcohol derivatives containing a ferrocenyl moiety were synthesized. In addition, six unexpected compounds, the hydroxyls of the title compounds, methylated by methanol, were obtained. The structures of all these new compounds were confirmed using 1H NMR spectra, 13C NMR, MS and elemental analyses. Some compounds were also confirmed with IR spectra. The antifungal and plant growth regulatory activities of the title compounds are discussed.