Synthesis of Novel 1H-Imidazol[1,2-a]Indeno[2,1-e]Pyridine-6(5H)-Ones Derivatives via a One-Pot Four-Component Condensation Reaction

• Published in: Journal of heterocyclic chemistry Vol. 53; no. 3; pp. 805 - 808
• Main Authors: Mohammadi, Ali A., Taheri, Salman, Amouzegar, Ali
• Format: Journal Article
• Language: English
• Published: HOBOKEN Blackwell Publishing Ltd 01.05.2016; Wiley; Wiley Subscription Services, Inc
• Subjects: 1-e]pyridine; 2-a]indeno; Alum; Chemistry; Chemistry, Organic; imidazol; imidazol[1,2‐a]indeno[2,1‐e]pyridine; Multi component reactions; Physical Sciences; Science & Technology; TOPOISOMERASES-I; BREAST-CANCER; EFFICIENT CATALYST; SOLVENT-FREE CONDITIONS; INHIBITORS; IMIDAZOPYRIDINE; WATER

1H‐imidazol[1,2‐a]indeno[2,1‐e]pyridine‐6(5H)‐ones derivatives were synthesized in a one‐pot four‐component condensation of corresponding aldehydes, 1,3‐indandione, diamine, and nitro ketene dithioacetal using KAl(SO4)2·12H2O (alum) as nontoxic, reusable, inexpensive and easily available catalyst in...