Diode laser spectroscopy based monitoring of pharmaceutical freeze drying: Linking measurements to critical process parameters

Freeze drying is used to produce dry solid from a solution to improve product stabilization. We have applied absorption spectroscopy to monitor water sublimation rates and determine product temperature during drying, a critical process parameter.

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Bibliographic Details
Published in2015 Conference on Lasers and Electro-Optics (CLEO) pp. 1 - 2
Main Author Kessler, William J.
Format Conference Proceeding
LanguageEnglish
Published OSA 01.05.2015
Subjects
Absorption
Diode lasers
Fluid flow measurement
Monitoring
Spectroscopy
Temperature measurement
Temperature sensors
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Summary:Freeze drying is used to produce dry solid from a solution to improve product stabilization. We have applied absorption spectroscopy to monitor water sublimation rates and determine product temperature during drying, a critical process parameter.
ISSN:2160-8989
2160-9004
DOI:10.1364/CLEO_AT.2015.AF1J.1