Osteogenic Sarcoma in Children
One hundred and thirty children less than 16 years of age with pathologically verified osteogenic (skeletogenic) sarcoma were seen during a 30-year period (1925-1955) with a minimum follow-up of ten years. This age group represents 23.6 per cent of the authors' total experience with skeletogeni...
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Published in | California medicine Vol. 103; no. 3; pp. 165 - 170 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
BMJ Publishing Group LTD
01.09.1965
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Subjects | |
Online Access | Get full text |
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Summary: | One hundred and thirty children less than 16 years of age with pathologically verified osteogenic (skeletogenic) sarcoma were seen during a 30-year period (1925-1955) with a minimum follow-up of ten years. This age group represents 23.6 per cent of the authors' total experience with skeletogenic sarcoma. The absolute survival for the entire series was 18.5 per cent at five years and 16.2 per cent at ten years. No child with an osseous tumor elsewhere than in an extremity had longterm survival. Amputation was the only “curative” method of therapy; 23 per cent of patients so treated were alive at five years and 20 per cent were alive at ten years. Radiation was never “curative” when used as the sole method of therapy, and treatment failure was higher in the group of patients who were treated with preoperative irradiation and then amputation than in the group treated by amputation alone. Prognosis varied with the size of the tumor—the smaller the better. The most important factor in prognosis was the histologic subgrouping of osteogenic sarcoma. No evidence was found to support a belief that there are considerable differences between skeletogenic sarcomas in children and in adults. |
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Bibliography: | ark:/67375/NVC-P3D6G492-B istex:1501460C8D513525317FE7D1A540A1F5060E059E PMID:14341315 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0008-1264 2380-9949 |