Convenient way to 5-Substituted 4-amino-2,3-dihydro-4H-1,2,4-triazole-3-thiones

Various 4-amino-2,3-dihydro-4H-triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced expenses.

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Bibliographic Details
Published inJournal of heterocyclic chemistry Vol. 44; no. 2; pp. 279 - 284
Main Authors Smicius, Romualdas, Burbulien, Milda Malvina, Jakubkiene, Virginija, Udrenaite, Emilija, Vainilavicius, Povilas
Format Journal Article
LanguageEnglish
Published PROVO HETERO CORPORATION 01.03.2007
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
HETEROCYCLES
DERIVATIVES
ANTIMICROBIAL ACTIVITY
1,2,4-TRIAZOLE
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Summary:Various 4-amino-2,3-dihydro-4H-triazoles with aromatic, aliphatic and heterocyclic substituents at the C(5) position were synthesized from corresponding esters and thiocarbohydrazide. This method allows the synthesis these heterocycles in a short time and at reduced expenses.
ISSN:0022-152X
DOI:10.1002/jhet.5570440201