ZrOCl2 Catalysed Chemoselective Conversion of Aldehydes to geminal-Diacetates and Their Cleavage: A Mild and Efficient Method
ZrOCl2 was found to be an effective Lewis acid catalyst for the solventless chemoselective conversion of aldehydes into geminal‐diacetates in high yields at room temperature. Regeneration of the aldehydes from the acetals was also achieved using the same catalyst in water. The beneficial effect of m...
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Published in | Chinese journal of chemistry Vol. 25; no. 10; pp. 1555 - 1558 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
01.10.2007
WILEY‐VCH Verlag Wiley |
Subjects | |
Online Access | Get full text |
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Summary: | ZrOCl2 was found to be an effective Lewis acid catalyst for the solventless chemoselective conversion of aldehydes into geminal‐diacetates in high yields at room temperature. Regeneration of the aldehydes from the acetals was also achieved using the same catalyst in water. The beneficial effect of microwave irradiation on the reaction was also described. Other advantages are the very low loading of catalyst, high yields achieved even on a gram scale, and considerably shortened reaction time compared to the conventional method. |
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Bibliography: | ark:/67375/WNG-LRNMRCX5-9 istex:578A4BDA699751C05473718DC7EE0BE30A438F0B ArticleID:CJOC200790286 |
ISSN: | 1001-604X 1614-7065 |
DOI: | 10.1002/cjoc.200790286 |