The cortical and sub-cortical network of sensory evoked response in healthy subjects

• Published in: 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Vol. 2013; pp. 5369 - 5372
• Main Authors: Muthuraman, M., Hellriegel, H., Groppa, S., Deuschl, G., Raethjen, J.
• Format: Conference Proceeding Journal Article
• Language: English
• Published: United States IEEE 01.01.2013
• Subjects: Coherence; Electric Stimulation; Electrodes; Electroencephalography; Electromyography; Frontal Lobe - physiology; Healthy Volunteers; Humans; Imaging; Magnetic Resonance Imaging; Median Nerve - physiology; Muscles; Nervous system; Somatosensory Cortex - physiology
• ISSN: 1094-687X; 1557-170X
• DOI: 10.1109/EMBC.2013.6610762

The aim of this study was to find the cortical and sub-cortical network responsible for the sensory evoked coherence in healthy subjects during electrical stimulation of right median nerve at wrist. The multitaper method was used to estimate the power and coherence spectrum followed by the source analysis method dynamic imaging of coherent sources (DICS) to find the highest coherent source for the basic frequency 3Hz and the complete cortical and sub-cortical network responsible for the sensory evoked coherence in healthy subjects. The highest coherent source for the basic frequency was in the posterior parietal cortex for all the subjects. The cortical and sub-cortical network comprised of the primary sensory motor cortex (SI), secondary sensory motor cortex (SII), frontal cortex and medial pulvinar nucleus in the thalamus. The cortical and sub-cortical network responsible for the sensory evoked coherence was found successfully with a 64-channel EEG system. The sensory evoked coherence is involved with a thalamo-cortical network in healthy subjects.