Quantitative estimation of electro-osmosis force on charged particles inside a borosilicate resistive-pulse sensor

Nano and micron-scale pore sensors have been widely used for biomolecular sensing application due to its sensitive, label-free and potentially cost-effective criteria. Electrophoretic and electroosmosis are major forces which play significant roles on the sensor's performance. In this work, we...

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Published in2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) Vol. 2016; pp. 4228 - 4231
Main Authors Ghobadi, Mostafa, Yuqian Zhang, Rana, Ankit, Esfahani, Ehsan T., Esfandiari, Leyla
Format Conference Proceeding Journal Article
LanguageEnglish
Published United States IEEE 01.08.2016
Subjects
Boron - chemistry
Electrochemical Techniques
Electrodes
Models, Theoretical
Nanopores
Osmosis
Silicates - chemistry
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Summary:Nano and micron-scale pore sensors have been widely used for biomolecular sensing application due to its sensitive, label-free and potentially cost-effective criteria. Electrophoretic and electroosmosis are major forces which play significant roles on the sensor's performance. In this work, we have developed a mathematical model based on experimental and simulation results of negatively charged particles passing through a 2μm diameter solid-state borosilicate pore under a constant applied electric field. The mathematical model has estimated the ratio of electroosmosis force to electrophoretic force on particles to be 77.5%.
ISSN:1557-170X
DOI:10.1109/EMBC.2016.7591660