A Fast Algorithm Aligning Multiple Microbial Genomic Sequences

To compare large genomic DNA sequences of related organisms and of different species, researchers need efficient methods to align many long sequences. We developed a new tool super multiple genome alignment (SMGA for short), specially for rapid multiple global alignment of genomic sequences. SMGA ca...

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Bibliographic Details
Published in2005 IEEE Engineering in Medicine and Biology 27th Annual Conference Vol. 2006; pp. 240 - 243
Main Authors Hu, Guangyue, Shen, Shiyi
Format Conference Proceeding Journal Article
LanguageEnglish
Published United States IEEE 2005
Subjects
Bioinformatics
DNA
Genomics
Humans
Large-scale systems
Mathematics
Mice
Microorganisms
Organisms
Sequences
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Summary:To compare large genomic DNA sequences of related organisms and of different species, researchers need efficient methods to align many long sequences. We developed a new tool super multiple genome alignment (SMGA for short), specially for rapid multiple global alignment of genomic sequences. SMGA can align a data set consisting of 50M of 9 enterobacterial genomic sequences in 40 minutes. Our method is faster when compared with other existing multiple sequences alignment method
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ISBN:0780387414
9780780387416
ISSN:1094-687X
1557-170X
1558-4615
DOI:10.1109/IEMBS.2005.1616388