Trisomy 8 in Philadelphia chromosome (Ph1)-negative cells in the course of Ph1-positive chronic myelocytic leukemia
A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph1), cells with trisomy 8 and Ph1, and c...
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Published in | Genes chromosomes & cancer Vol. 4; no. 3; p. 269 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
01.04.1992
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Subjects | |
Online Access | Get more information |
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Summary: | A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph1), cells with trisomy 8 and Ph1, and cells with trisomy 8 as the sole anomaly. |
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ISSN: | 1045-2257 1098-2264 |
DOI: | 10.1002/gcc.2870040314 |