A Computationally Efficient Method to Quantify the Biometric Properties of Ventricular Repolarization Irregularities in Healthy and Diseased Human Subjects

Repolarization heterogeneity expressed by QT interval prolongation and abnormal temporal dynamics of the QT interval time series is an important factor in relation to coronary heart disease and lethal arrhythmias. Based on our observations, the calculation of window correlation between the mean and...

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Bibliographic Details
Published inComputing in cardiology Vol. 45; pp. 1 - 4
Main Author Palhalmi, Janos
Format Conference Proceeding
LanguageEnglish
Published Creative Commons Attribution 01.09.2018
Subjects
Color
Correlation
Diseases
Feature extraction
Heart beat
Microsoft Windows
Time series analysis
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Summary:Repolarization heterogeneity expressed by QT interval prolongation and abnormal temporal dynamics of the QT interval time series is an important factor in relation to coronary heart disease and lethal arrhythmias. Based on our observations, the calculation of window correlation between the mean and variance of features extracted from QT interval time series can reveal natural and disease specific fluctuation patterns. Our algorithm is potentially a sensitive biometric measure to quantify personalized differences and the properties of repolarization heterogeneity, and also a potential biomarker to characterize disease specific QT interval temporal dynamics.
ISSN:2325-887X
DOI:10.22489/CinC.2018.080