Biology-inspired visualization of morphogenetic motion in the zebrafish endoderm

Effective visualization of large, multidimensional image data is a key instrument for data exploration in biological and medical applications. We propose a method to visualize motion patterns on a spherical surface, illustrated for the example of the zebrafish embryo. In particular, we analyze cellu...

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Published in2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI) pp. 925 - 929
Main Authors Thierbach, Konstantin, Shah, Gopi, Glauche, Ingmar, Huisken, Jan, Roeder, Ingo, Scherf, Nico
Format Conference Proceeding Journal Article
LanguageEnglish
Published IEEE 01.04.2016
Subjects
Cellular
Convergence
Data visualization
Embryo
embryogenesis
Embryos
endoderm
Exploration
Formations
gastrulation
Medical imaging
Representations
Sociology
Statistics
tissue formation
Visualization
Zebrafish
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Summary:Effective visualization of large, multidimensional image data is a key instrument for data exploration in biological and medical applications. We propose a method to visualize motion patterns on a spherical surface, illustrated for the example of the zebrafish embryo. In particular, we analyze cellular motion by integrating prior knowledge about the underlying biological process and show how this improves visualization and connects to the conceptional description of the gastrulation process. We conclude that specialized visualizations are necessary to match data representation with conceptional ideas and to get a more intuitive understanding of the design principles of embryonic tissue formation.
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SourceType-Conference Papers & Proceedings-2
ISSN:1945-8452
DOI:10.1109/ISBI.2016.7493416