New GABAA receptor alpha5 subunit gene polymorphism that may confound genotyping

• Published in: American journal of medical genetics. Part B, Neuropsychiatric genetics Vol. 129B; no. 1; pp. 27 - 28
• Main Authors: Vaquero, C., Baca-Garcia, E., Diaz-Sastre, C., Perez-Rodriguez, M.M., Navio Acosta, M., Saiz-Ruiz, J., de Leon, J., Fernandez-Piqueras, J.
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15.08.2004
• Subjects: Base Sequence; Dinucleotide Repeats - genetics; DNA - chemistry; DNA - genetics; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; GABA; GABRA5; Genotype; Humans; polymorphism; Polymorphism, Genetic; Polymorphism, Single-Stranded Conformational; Protein Subunits - genetics; Receptors, GABA-A - genetics; Spain; Spain

We report the discovery of a new GABAA receptor alpha5 subunit gene polymorphism close to the polymorphism described by Glatt et al. (GT)5GCGTGC(GT)21. This new polymorphism is of great importance, because it means that non‐denaturing acrylamide gels used to separate the different alleles of the pol...