Guidelines for Small Size Samples Biostatistics in Current Medical Practice

The present study aims at bringing useful guidelines to a physician for determining the sample size when designing any research project. The sample size is an estimate of the number of patients determined in concordance with the objectives and the budget of the project. This paper presents several w...

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Bibliographic Details
Published in2019 E-Health and Bioengineering Conference (EHB) pp. 1 - 4
Main Authors Seritan, George Calin, Adochiei, Felix-Constantin, Enache, Bogdan-Adrian, Petroiu-Andruseac, Gladiola, Enache, Cristina-Daniela, Dascultu, Dana Adriana, Becheanu, Cristina Adriana, Ulmeanu, Alexandru
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.11.2019
Subjects
Bayesian methods
clinical trials
sample size determination
small sample size
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Summary:The present study aims at bringing useful guidelines to a physician for determining the sample size when designing any research project. The sample size is an estimate of the number of patients determined in concordance with the objectives and the budget of the project. This paper presents several ways for sample size determination i.e. classic methods, Bayesian approach, dedicated software. All of them are analyzed considering that the end-user is not a statistician, but a doctor and pointers for choosing the best way when dealing with a small SS are highlighted.
ISSN:2575-5145
DOI:10.1109/EHB47216.2019.8970086