Candida

• Published in: Molecular Detection of Human Fungal Pathogens pp. 578 - 595
• Format: Book Chapter
• Language: English
• Published: United Kingdom CRC Press 2011; Taylor & Francis Group
• Subjects: FAMILY, HOME AND PRACTICAL INTERESTS; Food & beverage technology; Molecular biology; RCLB; 18S rRNA PCR; Invasive Disease; QiaAmp Tissue Kit; Faststart Taq DNA Polymerase; Reverse Transcriptase PCR; Multiplex PCR Reaction; Surgical ICU Patient; DNA Extraction Process; Molecular Grade Water; Surgical ICU; Multiplex PCR; Free DNA; Candida Species; Ba lE; DNA Extraction; White Cell; Conventional PCR; Fg DNA; 18S rRNA; SAPs; Candidal Disease; Clinical Specimens; Candida Cultures
• ISBN: 1439812403; 9781439812402
• DOI: 10.1201/b11375-68

Candida remains the most common cause of fungal disease worldwide with infections ranging from super–cial candidosis of mucosal membranes requiring “over-the-counter” pharmaceutical intervention to life-threatening invasive disease necessitating extensive medical, even surgical treatment. An improved awareness of invasive disease and an increasing susceptible population are countered by the availability of effective prophylaxis and limited techniques for accurate diagnosis. The incidence of disease is, at best, described as steady but varies geographically and is in¼uenced by general hospital practice. Indeed, comparison of incidence between countries is dif–cult. For countries without surveillance programs or the capacity to diagnose the disease using conventional techniques, the incidence may be greatly underestimated.