KAl(SO4)2·12H2O (Alum) Catalyzed One-Pot Three-Component Synthesis of 2-Alkyl and 2-Aryl-4(3H)-quinazolinone under Microwave Irradiation and Solvent Free Conditions

• Published in: Chinese journal of chemistry Vol. 29; no. 9; pp. 1982 - 1984
• Main Authors: Mohammadi, Ali A., Sadat Hossini, S. S.
• Format: Journal Article
• Language: English
• Published: Weinheim WILEY-VCH Verlag 01.09.2011; WILEY‐VCH Verlag; Wiley Subscription Services, Inc
• Subjects: 4(3H)-quinazolinone; ammonium acetate; isatoic anhydride; microwave-assisted reactions; multi component; orthoesters

Twenty 2,3‐disubstituted‐4(3H)‐quinazolinones were synthesed by one‐pot three‐component method with isatoic anhydride, orthoesters and amines as raw materials in the presence of KAl(SO4)2·12H2O (Alum) under microwave irradiation and solvent‐free conditions. 6‐Bromo‐2‐propyl‐3‐p‐tolylquinazolin‐4(3H)...