Heterogeneous Copper-Catalyzed Synthesis of Bioactive Heterocycles

• Published in: Heterogeneous Catalysis pp. 112 - 145
• Main Authors: Ameta, Ph.D., K.L., Penoni, Andrea
• Format: Book Chapter
• Language: English
• Published: United Kingdom CRC Press 2015; Taylor & Francis Group
• Subjects: Medical research; Organic chemistry; BDC; PMEI; NHC; Bimetallic Catalyst; Bioactive Heterocycles; Huisgen Cycloaddition; Domino Reactions; NNS; Arylboronic Acids; Microwave Irradiation Conditions; Aryl Halides; CuFe2O4; OHR; R1 R2; Simple Ltration; Azide Alkyne Cycloaddition; Excellent Yields; Click Reactions; Catalytic System; Terminal Alkynes; CuO Nanoparticles; BPA; Cycloaddition; Heterogeneous Catalyst; AcO AcO
• ISBN: 1466594829; 9781466594821
• DOI: 10.1201/b17418-8

Developing novel catalytic systems that meet the requirements of green chemistry has emerged as one of the most attractive and challenging subjects in chemistry.In the last two decades, copper catalysis has been intensively utilized for numerous useful transformations including oxidation (Diaz-Requejo et al., 2000; Kantam et al., 2009a), cycloaddition (Reymond and Cossy, 2008; Hein and Fokin, 2010), crosscoupling (Ma and Cai, 2008), C-H activation (Daugulis et al., 2009; Wendlandt et al., 2011), domino reactions (Liu and Wan, 2011, 2012), and so on. These Cu-mediated reactions are also involved in many valuable synthetic applications such as the assembly of biologically and medicinally useful molecules.