Point-Spread Function Reduction through High-Harmonic Generation Deactivation

Super-resolution microscopy is a powerful tool to resolve processes on the nm-scale. Label-free techniques are the preferred choice for imaging of unstained biological samples and nanoscale semiconductor devices [1]. Here a new microscopy technique is proposed based on generation of harmonics in sol...

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Bibliographic Details
Published inConference on Lasers & Electro-Optics Europe & International Quantum Electronics Conference (Online) p. 1
Main Authors Murzyn, Kevin, Guery, Leo, Nie, Zhonghui, van der Geest, Maarten, Kraus, Peter M.
Format Conference Proceeding
LanguageEnglish
Published IEEE 26.06.2023
Subjects
Europe
Harmonic analysis
Modulation
Nanoscale devices
Semiconductor devices
Solids
Superresolution
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Summary:Super-resolution microscopy is a powerful tool to resolve processes on the nm-scale. Label-free techniques are the preferred choice for imaging of unstained biological samples and nanoscale semiconductor devices [1]. Here a new microscopy technique is proposed based on generation of harmonics in solid materials and the deactivation of these harmonics using a second light beam. The temporal modulation of harmonics using light pulses is a subject of current research in a variety of materials, from strongly correlated [2], to 2D [3]. Using an approach similar to STED microscopy [4] this effect can be used to improve the resolution without labeling the sample.
ISSN:2833-1052
DOI:10.1109/CLEO/Europe-EQEC57999.2023.10232124