Synthesis of 3,4-Dialkyl-5-(1-oxo-ethyl)-3H-thiazole-2-thiones Derivatives and Their Pesticidal Activity

• Published in: Journal of heterocyclic chemistry Vol. 50; no. 5; pp. 1083 - 1088
• Main Authors: Eliazyan, Karine A., Knyazyan, Aram M., Pivazyan, Vergush A., Ghazaryan, Emma A., Harutyunyan, Siranush V., Yengoyan, Aleksandr P.
• Format: Journal Article
• Language: English
• Published: Hoboken Blackwell Publishing Ltd 01.09.2013; Wiley Subscription Services, Inc
• Subjects: NMR; Nuclear magnetic resonance
• ISSN: 0022-152X; 1943-5193
• DOI: 10.1002/jhet.1596

By interaction of N‐methyl(ethyl)‐dithiocarbamate sodium salt with 3‐chloro‐pentane‐2,4‐dion the 1‐(3‐alkyl‐4‐methyl‐2‐thioxo‐2,3‐dihydro‐thiazol‐5‐yl)‐ethanones 1, 2 and corresponding oximes 7, 8 were synthesized. On the basis of the mentioned compounds hydrazono (3, 4), ureayl and thioureayl (5, 6) derivatives, substituted oximes (9, 10) and azinyl oximes (11, 12) were obtained. The structures of synthesized compounds were confirmed by proton nuclear magnetic resonance spectroscopy and elemental analysis. The pesticidal activities of synthesized compounds were studied. Some of the synthesized compounds simultaneously have shown growth stimulant and fungicidal activity.