Development of a fully rotational non-contact fluorescence tomographer for small animals

We present herein the development of a fully 360/spl deg/ rotatable fluorescence tomography system for small animals without the use of source and detector fibers, or optically matching fluids. The setup consists of a cooled CCD camera coupled to a wide-angle objective and an axially moveable, colli...

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Bibliographic Details
Published inIEEE Nuclear Science Symposium Conference Record, 2005 Vol. 4; pp. 2391 - 2393
Main Authors Schulz, R.B., Echner, G., Ruhle, H., Stroh, W., Vierling, J., Vogt, T., Peter, J., Semmler, W.
Format Conference Proceeding
LanguageEnglish
Published IEEE 2005
Subjects
Animals
Charge coupled devices
Charge-coupled image sensors
Fiber lasers
Fluorescence
Optical collimators
Optical coupling
Optical detectors
Optical fibers
Tomography
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Summary:We present herein the development of a fully 360/spl deg/ rotatable fluorescence tomography system for small animals without the use of source and detector fibers, or optically matching fluids. The setup consists of a cooled CCD camera coupled to a wide-angle objective and an axially moveable, collimated laser source integrated within a rotating light-tight chamber. The system's capability to acquire and reconstruct high density datasets is demonstrated with experimental results from phantoms.
ISBN:0780392213
9780780392212
ISSN:1082-3654
2577-0829
DOI:10.1109/NSSMIC.2005.1596814