Detecting single molecule on bioenabled optofluidic biosensors by Inkjet printing

We developed an innovative approach to continuously deliver picoliter volume droplets onto bioenabled optofluidic biosensors. The ultra-hydrophilic diatom surface concentrates molecules in the solution as the solvent evaporates, which enables single molecule detection by SERS.

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Bibliographic Details
Published in2016 Conference on Lasers and Electro-Optics (CLEO) pp. 1 - 2
Main Authors Xianming Kong, Yuting Xi, LeDuff, Paul, Ye Liu, Li-Jing Cheng, Rorrer, Gregory L., Wang, Alan X.
Format Conference Proceeding
LanguageEnglish
Published OSA 01.06.2016
Subjects
Biosensors
Fluorescence
Glass
Printing
Raman scattering
Substrates
Surface treatment
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Summary:We developed an innovative approach to continuously deliver picoliter volume droplets onto bioenabled optofluidic biosensors. The ultra-hydrophilic diatom surface concentrates molecules in the solution as the solvent evaporates, which enables single molecule detection by SERS.
DOI:10.1364/cleo_si.2016.sw1g.4