Periodic Gold Nanohole Arrays Fabricated by Interference Lithography for Optical-Diffraction Biosensing

In this work, an optical-diffraction biosensor consisted of gold nanohole arrays was fabricated by interference lithography and lift-off process. The transmitted first diffraction order intensity of different streptavidin concentrations was analysed using a 458 nm wavelength and a photodetector conn...

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Bibliographic Details
Published in2018 International Conference on Optical MEMS and Nanophotonics (OMN) pp. 1 - 2
Main Authors Thesing, A., Avila, L. F., Armas, L. E. G., Valsecchi, C., Menezes, J. W.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.07.2018
Subjects
Biomedical optical imaging
biosensing
Biosensors
gold nanohole arrays
Immune system
interference lithography
Optical diffraction
Optics
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Summary:In this work, an optical-diffraction biosensor consisted of gold nanohole arrays was fabricated by interference lithography and lift-off process. The transmitted first diffraction order intensity of different streptavidin concentrations was analysed using a 458 nm wavelength and a photodetector connected to an oscilloscope. The biosensor limit of detection (LOD) was found to be 122 ng.mL −1 . The possibility of real time measurements and the high sensibility achieved demonstrate the great potential of the device.
DOI:10.1109/OMN.2018.8454549