Starch-Based Polymeric Biomaterial: Drug Delivery

Biomaterials are generally natural substances apart from food or drugs present in therapeutic or diagnostic systems that are in contact with tissue or biological uids.1 Polysaccharide-derived polymers display perfect biocompatibility and biodegradability, which are the basic requisites for polymers...

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Bibliographic Details
Published inHandbook of Encapsulation and Controlled Release pp. 599 - 606
Format Book Chapter
LanguageEnglish
Published CRC Press 2016
Subjects
STMP
Pharmaceutical Formulation Development
Modied Starches
Degradable Starch Microspheres
Plasma Volume Expander
SSG
Dosage Form
Pregelatinized Starch
Drug Delivery
Macromolecular Substances
Controlled Drug Delivery Applications
Solid Dosage Form Development
Acetic Anhydride
Metastatic Liver Tumors
Slow Release
Gene Delivery
Nanoparticle Matrix
Native Starch
Starch Binder
Starch Granules
Phosphoryl Chloride
Starch Nanoparticle
Solid Dosage Form
Sodium Tri-meta Phosphate
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Summary:Biomaterials are generally natural substances apart from food or drugs present in therapeutic or diagnostic systems that are in contact with tissue or biological uids.1 Polysaccharide-derived polymers display perfect biocompatibility and biodegradability, which are the basic requisites for polymers used as biomaterials. In carbohydrate-based polymeric systems, the drug is embedded in a polymer matrix and surgically implanted. The matrix may be biodegradable or nonbiodegradable. Hydrophilic polysaccharide carriers remain a highly popular design of modied release dosage form. Drug delivery systems containing polysaccharide excipient system was found to be capable of assuming different formulations and use in process methods to provide a variety of different release modalities independent of matrix-dimension.
DOI:10.1201/b19038-37