Drug-eluting stent with rhombic-shape reservoirs for drug delivery

A novel drug-eluting stent with rhombic-shape drug reservoirs is proposed, aimed at providing smart drug delivery and longer fatigue life. By creating the rhombic-shape reservoirs, a stent could increase its total drug capacity and improves its stress distribution for fatigue life enhancement. Simul...

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Bibliographic Details
Published in2016 International Conference on Applied System Innovation (ICASI) pp. 1 - 4
Main Authors Yen-Ting Wang, Yi-Ping Wang, Tzu-Yuan Lin, Chien-Erh Lin, Hao-Ming Hsiao
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.05.2016
Subjects
Analytical models
cardiovascular disease
Decision support systems
depot stent
drug-eluting stent
Fatigue
Finite element analysis
rhombic-shape drug reservoir
smart drug delivery
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Summary:A novel drug-eluting stent with rhombic-shape drug reservoirs is proposed, aimed at providing smart drug delivery and longer fatigue life. By creating the rhombic-shape reservoirs, a stent could increase its total drug capacity and improves its stress distribution for fatigue life enhancement. Simulation results showed that the total drug capacity of our stent could be significantly increased without sacrificing its fatigue life. This is astonishing considering that the stent mechanical integrity could be deteriorated by creating channels on the stent structure.
DOI:10.1109/ICASI.2016.7539756