Spatiotemporal Image Analysis for the Study of Cardiac Activity in Zebrafish Embryos

We address the problem of the quantitative cardiac activity analysis at early development stages. For this purpose, we have assembled an experimental setup for bright field microscopic imaging and analyzed Zebrafish embryos before hatching. We have developed and validated an image processing techniq...

Full description

Saved in:
Bibliographic Details
Published in2020 Wave Electronics and its Application in Information and Telecommunication Systems (WECONF) pp. 1 - 4
Main Authors Machikhin, A. S., Burlakov, A. B., Volkov, M. V., Khokhlov, D. D., Potemkin, A. V.
Format Conference Proceeding
LanguageEnglish
Published IEEE 01.06.2020
Subjects
cardiac activity
cardiovascular visualization
digital image processing
Embryo
Heart
Heart beat
Image analysis
in-vivo imaging
Microscopy
Optical imaging
photoplethysmography
Shape
zebrafish
Online AccessGet full text

Cover

More Information
Summary:We address the problem of the quantitative cardiac activity analysis at early development stages. For this purpose, we have assembled an experimental setup for bright field microscopic imaging and analyzed Zebrafish embryos before hatching. We have developed and validated an image processing technique for the spatiotemporal analysis of the obtained data. We demonstrate that the proposed technique provides quantitative information about the cardiac activity including heartbeat rate and heart shape.
DOI:10.1109/WECONF48837.2020.9131481