Design and analysis of microneedle array for transdermal drug delivery

MEMS-based transdermal delivery systems, such as microneedle arrays, allow for a painless administration of fluids into the skin while ensuring a desired yield. There are several benefits to drug delivery via transdermal application, including better patient compliance, reduced fluctuations in plasm...

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Bibliographic Details
Published in2022 8th International Conference on Smart Structures and Systems (ICSSS) pp. 1 - 4
Main Authors Lingaraja, D, Kumar, S Praveen, Ram, G Dinesh, Ramya, S
Format Conference Proceeding
LanguageEnglish
Published IEEE 21.04.2022
Subjects
Biochemistry
Biological system modeling
Drug delivery
Etching
Intellisuite and Reynold's number
Microneedle array
Shape
Skin
Titanium
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Summary:MEMS-based transdermal delivery systems, such as microneedle arrays, allow for a painless administration of fluids into the skin while ensuring a desired yield. There are several benefits to drug delivery via transdermal application, including better patient compliance, reduced fluctuations in plasma drug profiles, decreased gastric irritation, decreased enzyme deactivation, avoided first-pass hepatic metabolism, and elimination of the pre-systematic first-pass effect. Intellisuite was used to accomplish the analysis and simulation of the microneedle.
DOI:10.1109/ICSSS54381.2022.9782256