Antidiabetic and Anti-obesity Properties of Moringa Species

• Published in: Biological and Pharmacological Properties of the Genus Moringa Vol. 1; pp. 173 - 193
• Main Authors: Picos-Salas, Manuel A., Montoya-Inzunza, Luis A., Elizalde-Romero, Cristina Alicia, Gutiérrez-Grijalva, Erick P.
• Format: Book Chapter
• Language: English
• Published: United Kingdom Routledge 2022; Taylor & Francis Group
• Edition: 1
• Subjects: Oleifera Leaves; Caffeoylquinic Acid; Moringa Leaf Extracts; 3T3 L1 Preadipocytes; High Total Flavonoid Content; ABTS Radical Scavenge; SSR Marker; Lipase Active Site; Anti-obesity Potential; Hydrophilic Extracts; High Antioxidant Ability; Moringa Plants; ORAC; Moringa Leaf; Pancreatic Lipase Inhibition; ATP Sensitive Potassium Channel; Methyl Heptadecanoate; Oleifera Leaf; Oleifera Extracts; Lipase Inhibition; Antidiabetic Properties; Anti-adipogenic Effect; DPPH Radical Scavenge; Anti-obesity Effects; Lipase Inhibition Effect
• ISBN: 9780367621407; 9780367623159; 0367621401; 0367623153
• DOI: 10.1201/9781003108863-10

Moringa plants are a rich source of phytochemicals and natural compounds with potential health-promoting effects in humans. Moringa has been used in folk medicine for many years, mostly as infusions from its leaves and stem barks. Nowadays, ethnopharmacological studies have shown the antidiabetic and anti-obesity potential of moringa chemicals. The main natural compounds found throughout the moringa plants are phenolic compounds, flavonoids, terpenoids, and alkaloids. These molecules have anti-obesity and antidiabetic capacity through action mechanisms, whether isolated or as raw moringa extracts. Some of them are summarized in this chapter. So far, available information needs further evidence on the precise mechanisms of action of moringa phytochemicals. We still do not know effective doses, pharmacokinetics are scarce, and toxicological reports for its safe use in humans are also needed.